iPSC Kits
Induced pluripotent stem cells (also known as iPS cells or iPSCs) hold great promise in research and regenerative medicine. They are not only similar to endogenous pluripotent stem cells with the capability of self-renewal and differentiation but also can be generated from multiple cell types in the body (such as fibroblasts and blood cells).
We provide two kinds of easy-to-use and highly efficient iPSC reprogramming kits, an episomal iPSC reprogramming kit and a retrovirus iPSC reprogramming kit. With these fully optimized reprogramming kits, you can generate iPSCs from different somatic cell types with high success rates.
Integration-free episomal vectors use the oriP/EBNA-1 backbone to generate footprint-free iPSC lines without viral integration.
VSV-G pseudotyped retrovirus delivers high reprogramming efficiency in dividing cells and supports iPSC generation from various tissues and cell types.
Episomal protocols have been successfully demonstrated with human dermal fibroblasts, PBMCs, bone marrow cells, and lymphoblast B cells.
Complementary Products:
EZStemTM Dissociation Solution
EZStemTM Freezing Medium
Kit Portfolio
Episomal Reprogramming Kit
Integration-free system Uses episomal vectors to avoid host genome integration, "footprint free."
Pluripotent properties: iPSCs exhibit ESC-like morphology and expression of pluripotency markers.
Integration-free system: Uses episomal oriP/EBNA-1 backbone vectors, avoiding host genome integration.
Versatile reprogramming: Demonstrated success with fibroblasts, bone marrow mononuclear cells, PBMCs, lymphoblast B cells, and disease-type cells.
Retrovirus Reprogramming Kit
Efficient reprogramming: Uses retroviral delivery for high reprogramming efficiency.
Versatile, self-renewing results: Produces human iPSCs with self-renewal and pluripotency, suitable for differentiating into all cell types.
Wide target range: Utilizes VSV-G pseudotyped retrovirus, effective across mammalian and non-mammalian cells.
Defined factors: Drives reprogramming through ectopic expression of Oct4, Sox2, Klf4, and c-Myc.